The science
Cellular energy declines when three systems fail: mitochondrial quality control deteriorates, respiratory chain function becomes inefficient, and metabolic flexibility is lost. When these systems break down, they accelerate aging and drive chronic disease. Targeted interventions that clear damaged mitochondria and restore energy production rebuild youthful function and resilience.
How mitochondrial dysfunction impacts healthspan
Interventions can help
Restore energy production
When mitochondria become damaged, they produce less energy while creating harmful waste products that accelerate aging. Methylene blue supports respiratory chain function to enhance cellular power generation and reduce oxidative stress.
Enhance quality control
Rapamycin and urolithin A activate cellular cleanup systems that remove damaged mitochondria and replace them with new, healthy ones, so restoring mitochondrial renewal helps rebuild energy production and reduce inflammation.
Improve metabolic flexibility
SGLT2 inhibitors and physical training in different metabolic zones enhance the ability to switch between different fuel sources, optimizing cellular adaptation to energy demands and improving resilience to support healthy aging throughout life.
Enhance quality control
Rapamycin and urolithin A activate cellular cleanup systems that remove damaged mitochondria and replace them with new, healthy ones, so restoring mitochondrial renewal helps rebuild energy production and reduce inflammation.
Restore energy production
When mitochondria become damaged, they produce less energy while creating harmful waste products that accelerate aging. Methylene blue supports respiratory chain function to enhance cellular power generation and reduce oxidative stress.
Improve metabolic flexibility
SGLT2 inhibitors and physical training in different metabolic zones enhance the ability to switch between different fuel sources, optimizing cellular adaptation to energy demands and improving resilience to support healthy aging throughout life.
Hear from our patients
Amazing effect on my mental clarity
The methylene blue has had an amazing effect on my mental clarity and focus and the ability to recall and put my thoughts together and my energy level is greater now too! Literally I’ve had overall just a sense of better well being.
James J
Remarkable Results in Just 3 Days
I just wanted to share how incredibly impressed I am with your methylene blue supplement. I’ve been taking a dose of approximately 16 mg, and within just three days, I’ve noticed a truly remarkable shift in my body.
Simon Levy
Great products!
Very happy with my experience, the methylene blue especially helps a ton with my adhd and ability to focus, looking forward to more products coming out in the future.
Brent Lindstrom
This stuff works!
I have been using the Oxytocin nasal spray for the last 3 months and definitely notice a difference in my mood, my joint aches/pains and I find I feel more relaxed day to day.
Dori T
Just wow
I’m ramping up my intranasal oxytocin protocol and I can’t believe the improvement it’s already making. I suffer from various conditions, and it’s making an impact on most of them. My pain, stress, and anxiety have taken a nosedive.
Ned Drummond
Go for the consultation if you have any doubts, bc you wont after!
Informative, professional, supportive, with an exceptional scope of knowledge. In a word, excellent.
Leslie D
Frozen shoulder gone for the first time
I had frozen shoulder that never went away. I finally have relief. They identified some biomarkers that we wanted to optimize and some other health goals to target. I have never had anyone spend so much time working with me individually.
Dave L
Grateful for Healthspan
Grateful for Healthspan! The most knowledgeable team. Helped me evaluate my labs and put together a plan to start optimizing things. I wish my current doctors were this thorough.
Danny
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Ahead of the field
“Rapamycin... is at the leading edge of a generation of research trials.”
“I would say that rapamycin is the current best-in-class for a longevity drug”
“Rapamycin... is at the leading edge of a generation of research trials.”
“I would say that rapamycin is the current best-in-class for a longevity drug”
“Rapamycin... is at the leading edge of a generation of research trials.”
“I would say that rapamycin is the current best-in-class for a longevity drug”
“Rapamycin... is at the leading edge of a generation of research trials.”
“I would say that rapamycin is the current best-in-class for a longevity drug”
Reviews
127 reviews
We study the studies
Healthspan longevity experts continuously review the latest clinical research, curating results to help deepen your understanding of aging science.