THE SCIENCE
Cognitive decline arises when neurons become hyper-inflammatory and cannot meet energy demands as mitochondrial function weakens. Damaged proteins build up and neurons atrophy, driving memory loss and accelerated aging. By calming inflammation and restoring energy metabolism, targeted interventions help protect brain function and preserve cognition.
Cellular drivers of cognitive decline and aging
Interventions can help
Restore Mitochondrial Function
Neurons require high energy to maintain connections and repair damage. Methylene blue, urolithin A, and AMPK activators enhance mitochondrial efficiency and reduce oxidative stress, improving energy supply and sustaining cognitive performance.
Reduce Neuroinflammation
Chronic inflammation in the brain damages neurons and disrupts signaling. Interventions like LDN and rapamycin calm overactive immune responses and microglial activation, helping to protect brain tissue and slow cognitive decline.
Enhance Autophagy
When protein clearance falters, misfolded and toxic proteins build up in neurons. Rapamycin, metformin, and our autophagy formulations reactivate cellular repair pathways, improving proteostasis and protecting neurons from degeneration.
Reduce Neuroinflammation
Chronic inflammation in the brain damages neurons and disrupts signaling. Interventions like LDN and rapamycin calm overactive immune responses and microglial activation, helping to protect brain tissue and slow cognitive decline.
Restore Mitochondrial Function
Neurons require high energy to maintain connections and repair damage. Methylene blue, urolithin A, and AMPK activators enhance mitochondrial efficiency and reduce oxidative stress, improving energy supply and sustaining cognitive performance.
Enhance Autophagy
When protein clearance falters, misfolded and toxic proteins build up in neurons. Rapamycin, metformin, and our autophagy formulations reactivate cellular repair pathways, improving proteostasis and protecting neurons from degeneration.
Hear from our patients
Amazing effect on my mental clarity
The methylene blue has had an amazing effect on my mental clarity and focus and the ability to recall and put my thoughts together and my energy level is greater now too! Literally I’ve had overall just a sense of better well being.
James J
Great products!
Very happy with my experience, the methylene blue especially helps a ton with my adhd and ability to focus, looking forward to more products coming out in the future.
Brent Lindstrom
Just wow
I’m ramping up my intranasal oxytocin protocol and I can’t believe the improvement it’s already making. I suffer from various conditions, and it’s making an impact on most of them. My pain, stress, and anxiety have taken a nosedive.
Ned Drummond
This stuff works!
I have been using the Oxytocin nasal spray for the last 3 months and definitely notice a difference in my mood, my joint aches/pains and I find I feel more relaxed day to day.
Dori T
Go for the consultation if you have any doubts, bc you wont after!
Informative, professional, supportive, with an exceptional scope of knowledge. In a word, excellent.
Leslie D
Grateful for Healthspan
Grateful for Healthspan! The most knowledgeable team. Helped me evaluate my labs and put together a plan to start optimizing things. I wish my current doctors were this thorough.
Danny
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Ahead of the field
“Rapamycin... is at the leading edge of a generation of research trials.”
“I would say that rapamycin is the current best-in-class for a longevity drug”
“Rapamycin... is at the leading edge of a generation of research trials.”
“I would say that rapamycin is the current best-in-class for a longevity drug”
“Rapamycin... is at the leading edge of a generation of research trials.”
“I would say that rapamycin is the current best-in-class for a longevity drug”
“Rapamycin... is at the leading edge of a generation of research trials.”
“I would say that rapamycin is the current best-in-class for a longevity drug”
Reviews
127 reviews
We study the studies
Healthspan longevity experts continuously review the latest clinical research, curating results to help deepen your understanding of aging science.