Mitophagy
Urolithin A + EGCG activates mitophagy, clears damaged mitochondria, and reduces oxidative stress for cellular energy and healthy aging.
Removes dysfunctional mitochondria so cells can renew their energy systems.
Healthy mitochondria help power neurons and support cognitive resilience.
Improved mitochondrial efficiency helps muscles generate energy more effectively during activity.
FUNCTIONAL BENEFITS
Stay sharp as you age
EGCG crosses the blood-brain barrier, supporting brain cell health
Supports amyloid-clearance pathways and neuronal resilience
Activates mitophagy, renewing mitochondria to maintain brain cell energy
the science
Enhanced Mitochondrial Renewal
1 Data derived from a preclinical study evaluating mitochondrial biogenesis gene expression following combined Urolithin A and EGCG treatment in an Alzheimer’s disease mouse model (hAbKI mice).
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Frequently asked questions
Urolithin A is a compound derived from the gut microbiota’s transformation of ellagitannins, which are found in foods like pomegranates, walnuts, and berries. It is renowned for its ability to enhance mitochondrial function and support longevity.
Healthspan recommends starting with 500 mg of Urolithin A daily, taken with meals. Depending on individual response and health goals, the dose can be increased to 1,000 mg.
Urolithin A promotes mitophagy, the selective removal of damaged mitochondria. This process helps improve mitochondrial efficiency, leading to better energy production, enhanced muscle endurance, and improved metabolic health.
Urolithin A can benefit individuals looking to improve muscle endurance, maintain cognitive health, enhance cardiovascular function, and prevent metabolic disorders like diabetes. It is also widely used for its anti-aging properties.
Urolithin A is well-tolerated by most individuals, though mild digestive discomfort such as bloating or nausea can occur at higher doses. Taking it with food can help minimize these effects.
While results may vary, most individuals experience improvements in muscle endurance and energy levels within 4-8 weeks. Long-term benefits for metabolic health and aging typically emerge after 12 weeks of consistent use.
It is recommended to consult with a healthcare provider before combining Urolithin A with other medications, particularly those that affect mitochondrial function or energy metabolism, such as metformin.
Yes, Urolithin A can be integrated with other Healthspan protocols, particularly those aimed at improving energy metabolism, muscle health, and longevity.
Urolithin A is not FDA-approved for any specific medical treatments. However, it has been granted Generally Recognized As Safe (GRAS) status by the FDA for use as a dietary supplement, particularly for its role in supporting mitochondrial health, enhancing muscle function, and promoting longevity. This designation indicates that Urolithin A is considered safe when used according to recommended guidelines.
Urolithin A is a compound derived from the gut microbiota’s transformation of ellagitannins, which are found in foods like pomegranates, walnuts, and berries. It is renowned for its ability to enhance mitochondrial function and support longevity.
Healthspan recommends starting with 500 mg of Urolithin A daily, taken with meals. Depending on individual response and health goals, the dose can be increased to 1,000 mg.
Urolithin A promotes mitophagy, the selective removal of damaged mitochondria. This process helps improve mitochondrial efficiency, leading to better energy production, enhanced muscle endurance, and improved metabolic health.
Urolithin A can benefit individuals looking to improve muscle endurance, maintain cognitive health, enhance cardiovascular function, and prevent metabolic disorders like diabetes. It is also widely used for its anti-aging properties.
Urolithin A is well-tolerated by most individuals, though mild digestive discomfort such as bloating or nausea can occur at higher doses. Taking it with food can help minimize these effects.
While results may vary, most individuals experience improvements in muscle endurance and energy levels within 4-8 weeks. Long-term benefits for metabolic health and aging typically emerge after 12 weeks of consistent use.
It is recommended to consult with a healthcare provider before combining Urolithin A with other medications, particularly those that affect mitochondrial function or energy metabolism, such as metformin.
Yes, Urolithin A can be integrated with other Healthspan protocols, particularly those aimed at improving energy metabolism, muscle health, and longevity.
Urolithin A is not FDA-approved for any specific medical treatments. However, it has been granted Generally Recognized As Safe (GRAS) status by the FDA for use as a dietary supplement, particularly for its role in supporting mitochondrial health, enhancing muscle function, and promoting longevity. This designation indicates that Urolithin A is considered safe when used according to recommended guidelines.