Rapamycin
One of the most comprehensive longevity interventions available, Rapamycin addresses several molecular processes at once to slow the aging process and promote cellular health.
Resets hyperactive mTOR signaling that accelerates aging back to youthful levels, slowing down biological aging at a cellular level.
Clears senescent cells and reduces their harmful inflammatory signals to restore healthier tissue function.
Stimulate your body's natural and essential cleaning process to clear cellular damage and maintain cellular health critical for longevity.
Go beneath the surface of aging
Dosing is everything
Included with your Rapamycin Protocol
Healthspan personalized treatment protocols include professional clinical support on an ongoing basis. With MySpan, you can track your progress in real time—upload photos, record changes, and monitor how your protocol responds to treatment, all in one place.
Healthspan personalized treatment protocols include professional clinical support on an ongoing basis. With MySpan, you can track your progress in real time—upload photos, record changes, and monitor how your protocol responds to treatment, all in one place.
Healthspan Members Get More
Take a holistic approach to remaining strong, active, and sharp as you age.
Personalized Rapamycin Protocol
Advanced lab work & analysis
Expert lifestyle coaching
Results tracking & optimizations
Hear from our patients
Nothing short of miraculous...
Osteoarthritis pains improved 97%, pain in my neck is gone! All this and Ive just entered week 4 of treatment with Rapamycin. Can hardly wait for week 8 to see how much more Ill be amazed!!
Paul Windhausen
My joint pain has got so much better.
I really appreciate how they review blood work with me and guide me through the process. My joint pain has got so much better. I am glad that they have figured a way to make Rapamycin more available
Stephanie
Labs, progress, and care. All dialed in.
Healthspan provides great care when prescribing Rapamycin alongside frequent lab tests and detailed progress monitoring
Jspflorida
Reviews
129 reviews
Frequently asked questions
Your protocol includes a fully personalized dosing plan based on lab data, free biomarker testing, access to high-bioavailability rapamycin, and direct guidance from our clinical support team. You’ll also get access to a personalized dashboard to monitor results and track changes in biological age, mTOR activity, and more.
Yes. We only source from certified pharmacies and validate the bioavailability of every batch. Rapamycin absorption varies—so we use pharmacokinetic testing standards like Tmax and Cmax to select the most reliable formulations.
Your panel includes key metabolic, inflammatory, and longevity biomarkers—ApoB, hs-CRP, IGF-1, insulin sensitivity, liver function, and more. These help us assess autophagy activation, mTOR activity, and aging trends.
We prioritize generic rapamycin for its proven absorption profile (3x higher than compounded). Compounded formulations are available in special cases but are not our first-line approach.
When dosed intermittently and monitored by our team, rapamycin can be used safely for long-term healthspan support. Weekly protocols are designed to avoid mTORC2 inhibition and minimize immune suppression.
You’ll typically start with 3mg weekly and titrate up based on labs. Most patients stabilize between 5–8mg/week. All doses are taken once per week—not daily—to optimize autophagy and avoid continuous mTOR inhibition.
We strongly recommend labs for dose optimization and to track effects on mTOR, autophagy, and inflammation. Your labs are included at no additional cost.
You do not need a separate physician. Our clinical support team handles onboarding, optimization, and regular lab reviews to guide your journey.
Yes—rapamycin was originally developed as an immunosuppressant for organ transplant recipients. In that setting, it’s used at high, continuous doses that inhibit both mTORC1 and mTORC2, leading to broad immune suppression. In contrast, longevity protocols use low, intermittent doses designed to selectively inhibit mTORC1 only, while sparing mTORC2. This preserves immune function and instead promotes beneficial effects like autophagy activation, cellular repair, and inflammation reduction.
Rapamycin may not be suitable for individuals with uncontrolled infections, severely impaired immune systems, recent major surgeries, or those who are pregnant or breastfeeding. All protocols are reviewed by a physician to ensure safety based on your health profile.
Your protocol includes a fully personalized dosing plan based on lab data, free biomarker testing, access to high-bioavailability rapamycin, and direct guidance from our clinical support team. You’ll also get access to a personalized dashboard to monitor results and track changes in biological age, mTOR activity, and more.
Yes. We only source from certified pharmacies and validate the bioavailability of every batch. Rapamycin absorption varies—so we use pharmacokinetic testing standards like Tmax and Cmax to select the most reliable formulations.
Your panel includes key metabolic, inflammatory, and longevity biomarkers—ApoB, hs-CRP, IGF-1, insulin sensitivity, liver function, and more. These help us assess autophagy activation, mTOR activity, and aging trends.
We prioritize generic rapamycin for its proven absorption profile (3x higher than compounded). Compounded formulations are available in special cases but are not our first-line approach.
When dosed intermittently and monitored by our team, rapamycin can be used safely for long-term healthspan support. Weekly protocols are designed to avoid mTORC2 inhibition and minimize immune suppression.
You’ll typically start with 3mg weekly and titrate up based on labs. Most patients stabilize between 5–8mg/week. All doses are taken once per week—not daily—to optimize autophagy and avoid continuous mTOR inhibition.
We strongly recommend labs for dose optimization and to track effects on mTOR, autophagy, and inflammation. Your labs are included at no additional cost.
You do not need a separate physician. Our clinical support team handles onboarding, optimization, and regular lab reviews to guide your journey.
Yes—rapamycin was originally developed as an immunosuppressant for organ transplant recipients. In that setting, it’s used at high, continuous doses that inhibit both mTORC1 and mTORC2, leading to broad immune suppression. In contrast, longevity protocols use low, intermittent doses designed to selectively inhibit mTORC1 only, while sparing mTORC2. This preserves immune function and instead promotes beneficial effects like autophagy activation, cellular repair, and inflammation reduction.
Rapamycin may not be suitable for individuals with uncontrolled infections, severely impaired immune systems, recent major surgeries, or those who are pregnant or breastfeeding. All protocols are reviewed by a physician to ensure safety based on your health profile.