Male TRT

4.9

|

12,000+ Patients Served

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The Healthspan team is very personable and knowledgeable.  They explain all of my biomarker results and how to achieve my longevity goals alongside my protocol.

Jim

Testosterone Injection

Long-acting injectable testosterone (cypionate) provides replacement therapy for men with clinically low testosterone. Care is delivered through Membership, including comprehensive labs and ongoing clinical oversight.

Restore energy, libido & vitality

Improves energy, libido, and vitality by restoring testosterone to physiologic levels.

Build muscle & improve body composition

Supports lean muscle mass, strength, bone density, and healthier fat distribution over time.

Support metabolic & cognitive health

Helps improve insulin sensitivity, focus, mood stability, and long-term metabolic health.

4.9

|

12,000+ Patients Served

Get ongoing care

HSA/FSA Eligible

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benefits

Your symptoms start with biology. So does progress.

Restores physiological testosterone levels, supporting energy, focus, and mood stability.

Supports lean muscle mass and bone density through anabolic signaling.

Improves libido and sexual performance by restoring androgen signaling.

Testosterone

Feel improvements quickly and sustained progress over months

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your complete care

Personalized TRT care starts with membership

Your dedicated Healthspan clinical care team reviews your health history and goals to determine eligibility and design your TRT protocol—personalized to your needs.
Track 70+ biomarkers including sex hormones across 9 biological systems with comprehensive lab panels to measure progress, identify trends, monitor hormone levels, and continuously optimize your protocol.
Your clinician monitors your symptoms and hormone levels, adjusting your dosage over time to optimize results while minimizing side effects, ensuring safe and effective treatment.
Work with your dedicated men's health expert on nutrition, movement, sleep, and daily habits to maximize your TRT results, manage symptoms, and build sustainable lifestyle changes.
Member benefits include personalized clinical evaluation, ongoing biomarker tracking, dose optimization and monitoring with your 1:1 longevity expert, comprehensive lab work, exclusive longevity content, and access to a like-minded community.
Total Care

One membership. Complete care.

GET STARTED FOR $68/MO + membership
common questions

Will I need lab work before and during TRT?

Yes. Lab testing is required before starting TRT and continues throughout care. Before treatment begins, we assess testosterone alongside related hormones and key health markers to identify root causes, confirm eligibility and establish an accurate baseline. Regular follow-ups track progress and help evolve treatment over time.

Who is testosterone replacement therapy for?

TRT is appropriate for men with clinically low testosterone due to structural or irreversible hypogonadism. It reliably restores levels into the physiologic range, resulting in symptom relief and long-term health protection. Because it replaces endogenous production, it’s best suited for men whose natural testosterone output is insufficient.

What side effects are associated with TRT?

TRT is generally well tolerated when appropriately prescribed and monitored. Some men experience mild side effects, such as acne, oily skin, mood changes, fluid retention, headache, or injection-site irritation. These effects are often dose-related and can usually be improved by adjusting the dose or injection schedule.

Why is a membership required for TRT at Healthspan?

TRT is prescribed through Membership for safe, effective treatment. Membership covers baseline hormone testing, regular follow-up labs, and clinician-guided dose management, along with coaching and lifestyle support focused on nutrition, exercise, sleep, and recovery. This approach helps ensure your health goals are reached.

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The physiology of TRT

HPG Axis Suppression

HPG Axis Suppression

Exogenous testosterone bypasses the HPG axis, increasing circulating levels while suppressing LH and endogenous production. Most appropriate when natural output is already insufficient.

Androgen Signaling

Androgen Signaling

Testosterone binds to androgen receptors throughout the body, regulating energy, libido, mood, muscle protein synthesis, and overall vitality.

Muscle & Bone Anabolism

Muscle & Bone Anabolism

Adequate testosterone supports lean muscle maintenance, strength, and bone density by promoting anabolic signaling in muscle and skeletal tissue.

Neurotransmitter Regulation

Neurotransmitter Regulation

Testosterone influences dopamine and serotonin signaling, supporting motivation, focus, emotional regulation, and mental clarity.

Metabolic Signaling

Metabolic Signaling

Testosterone plays a role in insulin sensitivity and fat distribution, helping support healthier body composition and metabolic function.

Erythropoiesis & Oxygen Delivery

Erythropoiesis & Oxygen Delivery

Testosterone stimulates red blood cell production, supporting oxygen delivery, stamina, and exercise capacity — which is why hematocrit is routinely monitored during therapy.

Hear from our patients

Explained my lab results clearly

Brandon did an excellent job explaining my lab results and answering my questions. He was kind enough to let me bounce protocol ideas off him and gave his honest opinion. Super professional and easy to talk to.

Laramie George

Finally feel supported in my health journey

The Healthspan team spent real time with me, listening and guiding me through labs and protocols. I’ve never had anyone be this thorough in helping me build a personalized plan.

Frank

Longevity protocols, energy, less pain

I am grateful to have found Healthspan. Since starting their research-backed, patient-centric protocols, I have more energy, less pain, and improved blood biomarkers.

Hiro Takata

Frequently asked questions

Who is testosterone replacement therapy (TRT) for?

Testosterone replacement therapy (TRT) is for men diagnosed with low testosterone based on blood testing and clinical symptoms. Candidates typically have below-normal testosterone levels along with symptoms such as low energy, reduced sex drive, erectile dysfunction, low mood, brain fog, or loss of muscle mass. A diagnosis requires appropriate lab testing and evaluation by a licensed provider.

TRT is not recommended for men who are actively trying to conceive or who wish to preserve fertility, as testosterone injections can suppress the body’s natural hormone signaling and reduce sperm production. In those situations, alternative treatment options may be more appropriate and can be discussed with a clinician.

What benefits can I expect from testosterone replacement therapy?

Many men experience improved energy, motivation, and overall vitality after starting TRT. Common benefits include increased libido and sexual function, improved mood and mental clarity, and gains in lean muscle mass and strength. Over time, testosterone therapy may also support healthier body composition, metabolic function, and bone density. Individual results vary and develop gradually.

How soon will I see results from TRT?

Results from testosterone replacement therapy typically occur in phases rather than all at once. Some men notice improvements in energy, mood, and libido within the first 1–2 weeks. Sexual function and fatigue often improve within the first month. Changes in muscle mass, fat distribution, and physical performance usually develop over several months, while bone density changes occur with longer-term treatment.

How is testosterone cypionate administered?

Testosterone cypionate is most commonly given as a subcutaneous injection, usually twice weekly, to maintain stable testosterone levels. Injections are typically done on consistent days each week. Dosing is individualized and adjusted over time based on lab results, symptoms, and clinical response. TRT is generally intended as a long-term therapy.

Will I need lab work before and during TRT?

Yes. Comprehensive lab testing is required before starting testosterone replacement therapy and continues throughout care. Before treatment begins, we assess testosterone alongside related hormones and key health markers to confirm eligibility and establish an accurate baseline.

During treatment, labs are repeated at regular intervals to guide dosing and monitor how testosterone therapy is affecting multiple systems in the body. In addition to testosterone levels, this includes markers related to blood counts, prostate health, metabolic function, and cardiovascular risk. This broader lab view allows clinicians to adjust treatment as needed and maintain safe, effective therapy over time.

At Healthspan, lab monitoring is a core part of membership and is designed to support long-term outcomes, not just short-term symptom relief.

What side effects and risks are associated with TRT?

Testosterone replacement therapy is generally well tolerated when appropriately prescribed and monitored. Some men experience mild side effects, such as acne, oily skin, mood changes, fluid retention, headache, or injection-site irritation. These effects are often dose-related and can usually be improved by adjusting the dose or injection schedule.

Less commonly, TRT may be associated with more serious risks, including elevated red blood cell counts (hematocrit), changes in cholesterol levels, blood clots, or prostate-related concerns, particularly in men with underlying risk factors. Because testosterone affects multiple systems in the body, regular lab monitoring and clinical follow-ups are essential to maintain safe testosterone levels and identify potential issues early.

At Healthspan, lab testing and ongoing oversight are a required part of care to help ensure treatment remains safe, effective, and appropriate over time.

How long do I need to stay on testosterone replacement therapy?

TRT is typically considered a long-term treatment. If therapy is discontinued, testosterone levels and related symptoms often return to baseline. Treatment plans are reviewed regularly, with comprehensive reassessment at least once per year.

How does testosterone medication fit into Healthspan membership?

Testosterone injections are prescribed as part of Healthspan membership, which provides the clinical and lifestyle support required for safe, effective testosterone replacement therapy. Medication is billed separately based on eligibility, while pricing remains consistent regardless of dose.

Membership covers baseline hormone testing, regular follow-up labs, and clinician-guided dose management, along with access to coaching and lifestyle support focused on nutrition, exercise, sleep, and recovery. This combined approach helps ensure testosterone therapy is managed as ongoing care — supporting both symptom improvement and long-term health.

Who is testosterone replacement therapy (TRT) for?

Testosterone replacement therapy (TRT) is for men diagnosed with low testosterone based on blood testing and clinical symptoms. Candidates typically have below-normal testosterone levels along with symptoms such as low energy, reduced sex drive, erectile dysfunction, low mood, brain fog, or loss of muscle mass. A diagnosis requires appropriate lab testing and evaluation by a licensed provider.

TRT is not recommended for men who are actively trying to conceive or who wish to preserve fertility, as testosterone injections can suppress the body’s natural hormone signaling and reduce sperm production. In those situations, alternative treatment options may be more appropriate and can be discussed with a clinician.

What benefits can I expect from testosterone replacement therapy?

Many men experience improved energy, motivation, and overall vitality after starting TRT. Common benefits include increased libido and sexual function, improved mood and mental clarity, and gains in lean muscle mass and strength. Over time, testosterone therapy may also support healthier body composition, metabolic function, and bone density. Individual results vary and develop gradually.

How soon will I see results from TRT?

Results from testosterone replacement therapy typically occur in phases rather than all at once. Some men notice improvements in energy, mood, and libido within the first 1–2 weeks. Sexual function and fatigue often improve within the first month. Changes in muscle mass, fat distribution, and physical performance usually develop over several months, while bone density changes occur with longer-term treatment.

How is testosterone cypionate administered?

Testosterone cypionate is most commonly given as a subcutaneous injection, usually twice weekly, to maintain stable testosterone levels. Injections are typically done on consistent days each week. Dosing is individualized and adjusted over time based on lab results, symptoms, and clinical response. TRT is generally intended as a long-term therapy.

Will I need lab work before and during TRT?

Yes. Comprehensive lab testing is required before starting testosterone replacement therapy and continues throughout care. Before treatment begins, we assess testosterone alongside related hormones and key health markers to confirm eligibility and establish an accurate baseline.

During treatment, labs are repeated at regular intervals to guide dosing and monitor how testosterone therapy is affecting multiple systems in the body. In addition to testosterone levels, this includes markers related to blood counts, prostate health, metabolic function, and cardiovascular risk. This broader lab view allows clinicians to adjust treatment as needed and maintain safe, effective therapy over time.

At Healthspan, lab monitoring is a core part of membership and is designed to support long-term outcomes, not just short-term symptom relief.

What side effects and risks are associated with TRT?

Testosterone replacement therapy is generally well tolerated when appropriately prescribed and monitored. Some men experience mild side effects, such as acne, oily skin, mood changes, fluid retention, headache, or injection-site irritation. These effects are often dose-related and can usually be improved by adjusting the dose or injection schedule.

Less commonly, TRT may be associated with more serious risks, including elevated red blood cell counts (hematocrit), changes in cholesterol levels, blood clots, or prostate-related concerns, particularly in men with underlying risk factors. Because testosterone affects multiple systems in the body, regular lab monitoring and clinical follow-ups are essential to maintain safe testosterone levels and identify potential issues early.

At Healthspan, lab testing and ongoing oversight are a required part of care to help ensure treatment remains safe, effective, and appropriate over time.

How long do I need to stay on testosterone replacement therapy?

TRT is typically considered a long-term treatment. If therapy is discontinued, testosterone levels and related symptoms often return to baseline. Treatment plans are reviewed regularly, with comprehensive reassessment at least once per year.

How does testosterone medication fit into Healthspan membership?

Testosterone injections are prescribed as part of Healthspan membership, which provides the clinical and lifestyle support required for safe, effective testosterone replacement therapy. Medication is billed separately based on eligibility, while pricing remains consistent regardless of dose.

Membership covers baseline hormone testing, regular follow-up labs, and clinician-guided dose management, along with access to coaching and lifestyle support focused on nutrition, exercise, sleep, and recovery. This combined approach helps ensure testosterone therapy is managed as ongoing care — supporting both symptom improvement and long-term health.

Optimize testosterone with science

Testosterone replacement therapy guided by labs, symptoms, and expert oversight to help your body restore production and regain vitality.

Get Started