Methylene blue is a synthetic compound that has recently attracted attention for its potential to support cellular energy production, reduce oxidative stress, and promote cognitive function as part of a broader longevity and wellness approach. It is a prescription medication used under the guidance of a healthcare professional.

At Healthspan, methylene blue is provided in capsule form with multiple dosing options to support personalized treatment. Our physicians help patients titrate their dose over time, starting with a low dose to assess tolerance and response. We offer 5mg, 10mg, 15mg, and 25mg capsules to help each patient arrive at the dose that is most appropriate for their needs. The protocol is often prescribed to be taken five days a week, balancing maximum benefits with safety considerations, and adjustments are made on an individual basis.

No, our prescription methylene blue is encapsulated, meaning it is swallowed whole and does not come into direct contact with your mouth or teeth. Unlike liquid or compounded forms that can cause staining, our carefully formulated capsules prevent any discoloration while ensuring optimal absorption.

Methylene blue can function as an alternative electron carrier within the mitochondria, which are the cell’s energy factories. By supporting more efficient ATP production and neutralizing free radicals, it may enhance overall energy levels, reduce oxidative damage, and contribute to healthier cellular function.

Early research, both preclinical and some clinical, suggests methylene blue may offer support for cognitive performance, neuroprotection, and improved energy metabolism. Individuals looking to optimize brain function, reduce oxidative stress, or support cellular vitality could find it useful. However, these applications remain largely off-label, and additional studies are ongoing.

Some people experience mild side effects such as headache, nausea, dizziness, or gastrointestinal discomfort. Individuals with G6PD deficiency should avoid methylene blue because of an increased risk of hemolytic anemia. It can also interact with certain antidepressants (like SSRIs and MAOIs) and other medications, potentially leading to serotonin syndrome. For safety, always inform our physician team of all medications you are taking.

While some notice subtle changes in mental clarity or energy within days to weeks, response times vary. Factors like dosage, overall health, and lifestyle habits can influence how quickly benefits are felt.

Yes, but you should consult our healthcare team before combining methylene blue with any other drugs, especially those affecting serotonin levels. It’s also vital for anyone with specific conditions such as G6PD deficiency to seek professional advice first.

In many cases, methylene blue can be combined with other Healthspan protocols. However, it’s essential to review your entire regimen with our physician team to ensure all therapies work safely and effectively together.

Methylene blue is FDA-approved for certain medical uses, including the treatment of methemoglobinemia. Its use for longevity, cognitive enhancement, and overall wellness is considered off-label. Individuals interested in exploring these potential benefits should discuss whether methylene blue is right for them with a qualified healthcare provider.