Senescence
Rapamycin
The most powerful tool to stop the acceleration of aging caused by mTOR dysfunction and cellular senescence.
The science of autophagy is the science of cellular rejuventation. Through the advent of autophagy-enhancing therapies, we can trigger the cell's ability to recycle toxic misfolded proteins and debris to consume for energy, and revitalize a cell.
The science of autophagy is the science of cellular rejuventation. Through the advent of autophagy-enhancing therapies, we can trigger the cell's ability to recycle toxic misfolded proteins and debris to consume for energy, and revitalize a cell.
CELLULAR DYSFUNCTION
Defective Cells and Their Toxic Proteins
One of the signature markers of an aged cell versus a young, healthy cell is the presence of inflammation. If you were to examine a biopsy of an older person's cells, you would see visible signs of inflammation, whereas the younger person's would be smoother and less inflamed. This is because as we get older, we have a higher proportion of inflammatory senescent cells. The most obvious example of this phenomenon is in neurodegenerative diseases like Alzheimer's where dysfunctional cells accumulate an assortment of toxic Tau proteins that cause the cell to be attacked by our immune system.
Deep Cleaning
Cellular Deep Cleaning
Autophagy enhancers like Metformin, Rapamycin, and Intermittent Fasting turn on the cell's autophagy machinery to consume these toxic proteins to turn into cellular energy. This is the cell's built-in programming to preserve energy in states of nutrient deprivation, while simultaneously creating a 'deep cleaning' phenomenon.
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