Low-dose naltrexone bottle and oxytocin nasal spray
01 Prescribed by
U.S.-licensed clinicians
02 Compounded by
Licensed U.S. pharmacy
03 Charged only
If prescribed

Per quarter

One shipment

  • 2treatments
  • 90day supply
  • 1start schedule

Two pathways, one plan

Complementary roles for persistent low energy.

  • (+) Inflammation
  • (+) Endorphins
  • (+) Stress recovery

Start schedule

  1. Week 1Start LDN
  2. Week 4Add oxytocin

[Fill once clinical approves the schedule.]

What’s in the box

One shipment · 90-day supply

Low-dose naltrexone
Clinician-selected dose
Oxytocin
Clinician-selected format
Start schedule
Written by your clinician
Clinician instructions
Included

Prescription only. Dispensed after clinician evaluation.

Low energy rarely has one cause.

Inflammation
Immune signaling in the nervous system.
Endorphins
Your body’s own pain and mood signaling.
Stress
How your body responds and recovers.

Myth

Low energy has one cause.

Fact

Fatigue often has more than one contributor.*

*Your clinician reviews your history to decide which treatments fit.

Low-dose naltrexone bottle and oxytocin nasal spray
01 Prescribed by
U.S.-licensed clinicians
02 Compounded by
Licensed U.S. pharmacy
03 Charged only
If prescribed

Per quarter

One shipment

  • 2treatments
  • 90day supply
  • 1start schedule

Two pathways, one plan

Complementary roles for persistent low energy.

  • (+) Inflammation
  • (+) Endorphins
  • (+) Stress recovery

Start schedule

  1. Week 1Start LDN
  2. Week 4Add oxytocin

[Fill once clinical approves the schedule.]

What’s in the box

One shipment · 90-day supply

Low-dose naltrexone
Clinician-selected dose
Oxytocin
Clinician-selected format
Start schedule
Written by your clinician
Clinician instructions
Included

Prescription only. Dispensed after clinician evaluation.

Low energy rarely has one cause.

Inflammation
Immune signaling in the nervous system.
Endorphins
Your body’s own pain and mood signaling.
Stress
How your body responds and recovers.

Myth

Low energy has one cause.

Fact

Fatigue often has more than one contributor.*

*Your clinician reviews your history to decide which treatments fit.

RX BUNDLE
CLINICIAN-PRESCRIBED

Energy & Recovery Bundle

LDN for inflammation and endorphins, oxytocin for stress recovery. Two prescription treatments, one plan.

4.9

|

12000+ patients served

inflammation

Immune signaling (LDN)

endorphins

Endorphin support (LDN)

recovery

Stress recovery (Oxytocin)

clinician-led

Evaluated for you

CHOOSE YOUR TREATMENT

CHOOSE YOUR TREATMENT

Billed quarterly. You’re only charged for what your clinician prescribes.

Start my evaluation — $180/mo

Free standard shipping

Prescribed by U.S.-licensed clinicians

Charged only if prescribed

Cancel or pause anytime

How LDN works

At low doses, naltrexone briefly blocks opioid receptors, which is thought to prompt your body to increase its own endorphin signaling. It may also calm immune activity in the nervous system linked to inflammation. It has been studied in small trials for pain and fatigue-related conditions, with mixed results.

How oxytocin works

Oxytocin acts on a different pathway, involved in how your body responds to and recovers from stress. Research on oxytocin and stress is early, and results vary.

Who it’s for

Adults with persistent low energy alongside stress, poor sleep, or pain. Your clinician reviews your history and medications to decide whether one or both treatments fit.

Who it’s not for

People who take or plan to take opioid pain medication, and people who are pregnant or breastfeeding. Your clinician screens for other conditions during your evaluation.

How you start

Both treatments ship together with a start schedule from your clinician. [Fill once clinical approves the schedule.]

ENERGY & RECOVERY

Two pathways, frominflammationto stress.

ENERGY & RECOVERY

Two pathways, from inflammation to stress.

The science, simply

Two treatments, Low-dose naltrexoneOxytocin nasal spraytwo systems.

LDN for inflammation and endorphins, oxytocin for stress recovery. One plan.

Proposed pathways · Off-label use

Immune & endorphin signalingStress response

Low-dose naltrexone · Day 1

Low-dose naltrexone

At low doses, naltrexone briefly blocks opioid receptors, which is thought to prompt your body to increase its own endorphin signaling. It may also calm immune activity linked to inflammation.

Oxytocin · Week 4

Oxytocin

Oxytocin acts on its own receptors, in a pathway involved in how your body responds to stress and recovers from it. Research on oxytocin and stress in people is still early, and results vary.

How your first
90 days work.

Day 1

Intake

Tell us about you

Complete your health history and medication list. Your payment method is saved, not charged.

Tell us about you

Complete your health history and medication list. Your payment method is saved, not charged.

Your clinician reviews

A U.S.-licensed clinician decides whether one or both treatments fit. You’re charged only for what’s prescribed.

Both arrive together

Your treatments ship in one box with your start schedule.

Add oxytocin

Following your schedule, you add the second treatment.

Your next quarter

Your treatments renew together. You can stop one, pause, or cancel anytime.

[Fill day and week labels from ops turnaround times and the clinical start schedule.]

What’s proven and what’s promising

Small trials

Evidence level

Studied in small trials for pain and fatigue-related conditions.

Results have been mixed, and larger controlled trials are limited. Proposed mechanisms include endorphin upregulation and reduced neuroimmune inflammation.

[Content team to source]

Low-dose naltrexone · Off-label use

Evidence ladder

Where the research on LDN stands

Mechanistic research
Proposed
Small trials
Current level
Large controlled trials
Limited

Results have been mixed, and larger controlled trials are limited. Proposed mechanisms include endorphin upregulation and reduced neuroimmune inflammation.

LDN and oxytocin haven’t been studied together in clinical trials.

Support for

  • inflammation
  • endorphins
  • stress recovery
  • energy

Clinician-prescribed

()

LDN and oxytocin, prescribed together and shipped in one box.

Bundle $180/mo · Charged only if prescribed

Common questions

When am I charged?

Only after your clinician prescribes. We save your payment method at signup but don’t charge until a treatment is approved.

What if I’m only eligible for one?

You receive that one at its standalone price. You’re never charged for a treatment you aren’t prescribed.

How do I start them?

Your box includes a start schedule from your clinician. [Update once clinical sets the schedule.]

Can I use this if I take opioid pain medication?

No. LDN blocks the effects of opioid medications, so this bundle isn’t a fit. Talk to your clinician about other options.

Can I stop one?

Yes. The bundle ends and the other treatment continues at its standalone price.

How much does it cost?

The bundle is $180/month, billed $540 quarterly. LDN alone is $65/month and oxytocin alone is $135/month. It’s cash pay.

When am I charged?

Only after your clinician prescribes. We save your payment method at signup but don’t charge until a treatment is approved.

What if I’m only eligible for one?

You receive that one at its standalone price. You’re never charged for a treatment you aren’t prescribed.

How do I start them?

Your box includes a start schedule from your clinician. [Update once clinical sets the schedule.]

Can I use this if I take opioid pain medication?

No. LDN blocks the effects of opioid medications, so this bundle isn’t a fit. Talk to your clinician about other options.

Can I stop one?

Yes. The bundle ends and the other treatment continues at its standalone price.

How much does it cost?

The bundle is $180/month, billed $540 quarterly. LDN alone is $65/month and oxytocin alone is $135/month. It’s cash pay.

Low-dose naltrexone and oxytocin are prescription medications available only after evaluation by a licensed clinician, who determines whether treatment is appropriate. Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality. Use of these medications for the symptoms described on this page is off-label. This page is educational and not medical advice; individual results vary.