Treatments
Personalized Protocolssmoke 1
Personalized Protocols
Labssmoke 2
Labs
Medicationssmoke 3
Medications
Supplementssmoke 1
Supplements
Learn more about
Explore
Optimization
Labssmoke 1
Labs
Coachingsmoke 2
Coaching
Personalized Protocolssmoke 3
Personalized Protocols
Learn more about
Goals
Optimize longevitysmoke 1
Optimize longevity
Fat losssmoke 2
Fat loss
Target joint painsmoke 3
Target joint pain
Grow stronger, healthier hairsmoke 1
Grow stronger, healthier hair
Boost energysmoke 2
Boost energy
Get healthier skinsmoke 3
Get healthier skin
About
Our Companysmoke 1
Our Company
Our Missionsmoke 2
Our Mission
How it Workssmoke 3
How it Works
Read our latest research
article imageSynergistic Effects of Rapamycin and Exercise for Maximizing Muscular Strength
article imageSuppressing Two Signals of Aging: Insights from the 2025 Rapamycin–Trametinib Study
article imageTargeting mTOR with Rapamycin Across Species: How Hypertrophic Cardiomyopathy Reversal in Cats Informs Human Cardiac Aging and Longevity
ResearchLog in
Get Started
Menu
  • Research
  • Log in
Get started
All studies
(sglt2)
Longevity
06 / 21 / 2025•29 MIN READ
The Case for Cyclical Longevity Protocols: How Rhythmic Activation of AMPK and Autophagy Reprograms Aging Cells
Brain
06 / 07 / 2025•20 MIN READ
The Energy Equation in Alzheimer’s Disease: Glucose-Driven Degeneration and Ketone-Driven Protection
Longevity
05 / 30 / 2025•32 MIN READ
The Mitochondrial Signature of Long COVID: What PRDX3 Is Trying to Tell Us—And How We Might Reverse It
Metabolism
04 / 26 / 2025•14 MIN READ
Pharmacological Fasting: How SGLT-2 Inhibitors Emulate Caloric Restriction to Target Key Longevity Pathways
Metabolism
03 / 08 / 2025•28 MIN READ
SGLT2 Inhibitors as Metabolic Senolytics: Clearing Senescent Cells to Combat Pathological Aging
Metabolism
01 / 25 / 2025•21 MIN READ
Mitochondria’s Paradoxical Role in Cancer Biology: Exploiting Metabolic Vulnerabilities for Therapeutic Targeting
Metabolism
01 / 18 / 2025•28 MIN READ
SGLT-2 Inhibitors in Aging and Healthspan: Surprising Mechanistic Insights Into Adipose Tissue Reduction, Lean Mass Preservation, and Longevity

Read the latest research reviews

Request The Longevity Blueprint to receive our weekly newsletter containing synopses of the latest clinical research.
Treatments
  • All Treatments
  • Personalized Protocols
  • Labs
  • Medications
  • Supplements
Top Treatments
Methylene Blue
Methylene Blue
Starting at $99/mo
Rapamycin
Rapamycin
Starting at $64/mo
Oxytocin
Oxytocin
Starting at $135/mo
ABOUT
  • Our Company
  • Our Mission
  • How It Works
SCIENCE
  • Articles
  • Senescence
  • Metabolism
  • Energy
SUPPORT
  • Contact Us
  • FAQs
  • Community
  • Log In
ABOUT
  • Our Company
  • Our Mission
  • How It Works
SCIENCE
  • Articles
  • Senescence
  • Metabolism
  • Energy
SUPPORT
  • Contact Us
  • FAQs
  • Community
  • Log In
contentImg
(Terms of Use)(privacy policy)(telehealth consent policy)
©2025 Healthspan.
All rights reserved.