Rapamycin is considered to be the most promising health span promoting interventions for its role in slowing down the formation of senescent cells through its inhibition of the mTOR complex 1 pathway. By slowing down the formation of senescent cells and their harmful effects, Rapamycin usage effectively delays the onset of age related diseases.

Dispensed by Licensed Pharmacy
Prescribed by functional medical physicians
Ongoing medical check-ins

The Pillars of Aging

What the Experts Are Saying (and doing)

Dr. David Sinclair

David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.

* Dr. David Sinclair is not involved with Healthspan and does not sell Metformin.

The Benefits of Rapamycin

Our Honest Assessment

Rapamycin shows the greatest potential as a medication that can slow down the formation of senescent cells and the corresponding age-related decline that comes with the higher ratio of dysfunctional senescent cells. Rapamycin binds directly to mTOR (complex 1) to induce cellular autophagy. By increasing autophagy through the inhibition mTOR, Rapamycin turns off the growth signals that drive senescent replication, reduces the inflammatory molecules (SASP) of senescent cells, and prevents healthy cells from becoming senescent cells.

More clinical trials need to be conducted to understand the proper dosing of Rapamycin for its off-lable use as an autophagy inducer. There is enough clinical data to understand the relative safety profile of Rapamycin when taken intermittently, however.

Great Potential, More Research Needed on Dosing Protocol

How it works

  • 1
    Online visit

    Start your online visit by completing our new patient intake and providing information about your medical history and lifestyle. The online evaluation takes about 15-20 minutes to complete.

  • 2
    Doctor review

    A functional medicine physician will review the information you provide and determine the prescription that best suits your needs. Scripts are available for 1 month, 3 month, and 6 month supplies

  • 3
    Free shipping

    If prescribed, your treatment will be shipped directly to you, and arrive within 5-7 business days. All orders are tracked electronically, and you will have access to tracking for each shipment.

  • 4
    Ongoing Care

    Our messaging portal is available 24/7 to communicate with our functional medicine providers. For any questions you have about treatment, you are able to communicate directly with your physician.