Autophagy - The Science Behind Intermittent Fasting

Intermittent Fasting is a very popular trend among celebrities, fitness coaches, and even your next door neighbor. Fasting in general is an ancient tradition, having been practiced by many cultures and religions over centuries.

Intermittent Fasting is a very popular trend among celebrities, fitness coaches, and even your next door neighbor. Fasting in general is an ancient tradition, having been practiced by many cultures and religions over centuries.

Fasting induces a large energy deficit, in the past our ancestors expended calories to obtain food. They hunted—and sometimes came back empty handed. They dug and climbed and rooted around and gathered. They walked, ran, stalked, jumped, lifted. Movement was a necessity.

They experienced energy deficits on a regular basis. And energy deficits, particularly sustained energy deficits, are the primary triggers for autophagy. Without energy deficits, you remain in fed mode and never quite hit the fasted mode required for autophagy.

What is autophagy?

Autophagy (or autophagocytosis) (from the Ancient Greek αὐτόφαγος autóphagos, meaning "self-devouring". The term in Greek literally means self eating.

Autophagy is a powerful evolutionary self-preservation mechanism through which the body can remove dysfunctional cells and toxic proteins responsible for many age related chronic diseases, and recycle parts of them toward cellular repair and cleaning.

Autophagy Inducers

Through the advent of autophagy enhancing therapies, we can trigger the cell's ability to recycle toxic misfolded proteins and debris to consume for energy, and revitalize a cell.

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